Review



sodium channel na v 1 6  (Alomone Labs)


Bioz Verified Symbol Alomone Labs is a verified supplier
Bioz Manufacturer Symbol Alomone Labs manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 96

    Structured Review

    Alomone Labs sodium channel na v 1 6
    ( A ) Genotype-dependent quantification of the density of nodes of Ranvier on longitudinal spinal cord sections of control ( Anln fl/fl ) and Anln cKO mice at P75 based on immunohistochemical analysis detecting the sodium channel <t>Na</t> <t>v</t> <t>1.6</t> as a marker. not significant (n.s.) according to unpaired two-tailed t-test; n = 4 mice per genotype; p=0.1985. ( B–F ) Immunohistochemical detection of the nodal marker Na v 1.6 (red) and the paranodal marker CASPR (green) on longitudinal spinal cord sections of control ( Anln fl/fl ) and Anln cKO mice at P75. Parameters measured for quantifications displayed in ( C–F ) are indicated in the merge of the control (in B ). p1/p2 = paranode length; d = axonal diameter at node; n = node length. ( C ) Genotype-dependent quantification of node length. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.6324. ( D ) Genotype-dependent quantification of paranode length. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.1927. ( E ) Ratio of node length and axonal diameter. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.5966. ( F ) Ratio of paranode length and axonal diameter. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.4603.
    Sodium Channel Na V 1 6, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 96/100, based on 154 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/na+v+1+6+sodium+channel/Anti-Nav1%2E6+(SCN8A)+Antibody/pmc06344079-140-33-38
    Average 96 stars, based on 154 article reviews
    sodium channel na v 1 6 - by Bioz Stars, 2026-10
    96/100 stars

    Images

    1) Product Images from "Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin"

    Article Title: Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin

    Journal: eLife

    doi: 10.7554/eLife.43888

    ( A ) Genotype-dependent quantification of the density of nodes of Ranvier on longitudinal spinal cord sections of control ( Anln fl/fl ) and Anln cKO mice at P75 based on immunohistochemical analysis detecting the sodium channel Na v 1.6 as a marker. not significant (n.s.) according to unpaired two-tailed t-test; n = 4 mice per genotype; p=0.1985. ( B–F ) Immunohistochemical detection of the nodal marker Na v 1.6 (red) and the paranodal marker CASPR (green) on longitudinal spinal cord sections of control ( Anln fl/fl ) and Anln cKO mice at P75. Parameters measured for quantifications displayed in ( C–F ) are indicated in the merge of the control (in B ). p1/p2 = paranode length; d = axonal diameter at node; n = node length. ( C ) Genotype-dependent quantification of node length. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.6324. ( D ) Genotype-dependent quantification of paranode length. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.1927. ( E ) Ratio of node length and axonal diameter. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.5966. ( F ) Ratio of paranode length and axonal diameter. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.4603.
    Figure Legend Snippet: ( A ) Genotype-dependent quantification of the density of nodes of Ranvier on longitudinal spinal cord sections of control ( Anln fl/fl ) and Anln cKO mice at P75 based on immunohistochemical analysis detecting the sodium channel Na v 1.6 as a marker. not significant (n.s.) according to unpaired two-tailed t-test; n = 4 mice per genotype; p=0.1985. ( B–F ) Immunohistochemical detection of the nodal marker Na v 1.6 (red) and the paranodal marker CASPR (green) on longitudinal spinal cord sections of control ( Anln fl/fl ) and Anln cKO mice at P75. Parameters measured for quantifications displayed in ( C–F ) are indicated in the merge of the control (in B ). p1/p2 = paranode length; d = axonal diameter at node; n = node length. ( C ) Genotype-dependent quantification of node length. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.6324. ( D ) Genotype-dependent quantification of paranode length. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.1927. ( E ) Ratio of node length and axonal diameter. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.5966. ( F ) Ratio of paranode length and axonal diameter. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.4603.

    Techniques Used: Immunohistochemical staining, Marker, Two Tailed Test

    Related Articles

    Staining:

    Article Title: Visual abnormalities associated with enhanced optic nerve myelination
    Article Snippet: .. Cryosections were stained using antibodies that recognize the Na V 1.6 sodium channel (anti-rabbit, Alomone labs, 1:500 dilution) or Contactin associated protein (Caspr; anti-mouse, gift from Dr. Matthew Rasband [Baylor College of Medicine, Houston, TX], 1:1000 dilution.). ..



    Similar Products

    96
    Alomone Labs sodium channel na v 1 6
    ( A ) Genotype-dependent quantification of the density of nodes of Ranvier on longitudinal spinal cord sections of control ( Anln fl/fl ) and Anln cKO mice at P75 based on immunohistochemical analysis detecting the sodium channel <t>Na</t> <t>v</t> <t>1.6</t> as a marker. not significant (n.s.) according to unpaired two-tailed t-test; n = 4 mice per genotype; p=0.1985. ( B–F ) Immunohistochemical detection of the nodal marker Na v 1.6 (red) and the paranodal marker CASPR (green) on longitudinal spinal cord sections of control ( Anln fl/fl ) and Anln cKO mice at P75. Parameters measured for quantifications displayed in ( C–F ) are indicated in the merge of the control (in B ). p1/p2 = paranode length; d = axonal diameter at node; n = node length. ( C ) Genotype-dependent quantification of node length. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.6324. ( D ) Genotype-dependent quantification of paranode length. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.1927. ( E ) Ratio of node length and axonal diameter. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.5966. ( F ) Ratio of paranode length and axonal diameter. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.4603.
    Sodium Channel Na V 1 6, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/na+v+1+6+sodium+channel/Anti-Nav1%2E6+(SCN8A)+Antibody/pmc06344079-140-33-38
    Average 96 stars, based on 1 article reviews
    sodium channel na v 1 6 - by Bioz Stars, 2026-10
    96/100 stars
      Buy from Supplier

    94
    Alomone Labs na v 1 6 sodium channel
    ( A ) Genotype-dependent quantification of the density of nodes of Ranvier on longitudinal spinal cord sections of control ( Anln fl/fl ) and Anln cKO mice at P75 based on immunohistochemical analysis detecting the sodium channel <t>Na</t> <t>v</t> <t>1.6</t> as a marker. not significant (n.s.) according to unpaired two-tailed t-test; n = 4 mice per genotype; p=0.1985. ( B–F ) Immunohistochemical detection of the nodal marker Na v 1.6 (red) and the paranodal marker CASPR (green) on longitudinal spinal cord sections of control ( Anln fl/fl ) and Anln cKO mice at P75. Parameters measured for quantifications displayed in ( C–F ) are indicated in the merge of the control (in B ). p1/p2 = paranode length; d = axonal diameter at node; n = node length. ( C ) Genotype-dependent quantification of node length. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.6324. ( D ) Genotype-dependent quantification of paranode length. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.1927. ( E ) Ratio of node length and axonal diameter. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.5966. ( F ) Ratio of paranode length and axonal diameter. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.4603.
    Na V 1 6 Sodium Channel, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/na+v+1+6+sodium+channel/Anti-NALCN%2FVGCNL1+Antibody/pmc04395475-190-8-14
    Average 94 stars, based on 1 article reviews
    na v 1 6 sodium channel - by Bioz Stars, 2026-10
    94/100 stars
      Buy from Supplier

    Image Search Results


    ( A ) Genotype-dependent quantification of the density of nodes of Ranvier on longitudinal spinal cord sections of control ( Anln fl/fl ) and Anln cKO mice at P75 based on immunohistochemical analysis detecting the sodium channel Na v 1.6 as a marker. not significant (n.s.) according to unpaired two-tailed t-test; n = 4 mice per genotype; p=0.1985. ( B–F ) Immunohistochemical detection of the nodal marker Na v 1.6 (red) and the paranodal marker CASPR (green) on longitudinal spinal cord sections of control ( Anln fl/fl ) and Anln cKO mice at P75. Parameters measured for quantifications displayed in ( C–F ) are indicated in the merge of the control (in B ). p1/p2 = paranode length; d = axonal diameter at node; n = node length. ( C ) Genotype-dependent quantification of node length. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.6324. ( D ) Genotype-dependent quantification of paranode length. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.1927. ( E ) Ratio of node length and axonal diameter. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.5966. ( F ) Ratio of paranode length and axonal diameter. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.4603.

    Journal: eLife

    Article Title: Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin

    doi: 10.7554/eLife.43888

    Figure Lengend Snippet: ( A ) Genotype-dependent quantification of the density of nodes of Ranvier on longitudinal spinal cord sections of control ( Anln fl/fl ) and Anln cKO mice at P75 based on immunohistochemical analysis detecting the sodium channel Na v 1.6 as a marker. not significant (n.s.) according to unpaired two-tailed t-test; n = 4 mice per genotype; p=0.1985. ( B–F ) Immunohistochemical detection of the nodal marker Na v 1.6 (red) and the paranodal marker CASPR (green) on longitudinal spinal cord sections of control ( Anln fl/fl ) and Anln cKO mice at P75. Parameters measured for quantifications displayed in ( C–F ) are indicated in the merge of the control (in B ). p1/p2 = paranode length; d = axonal diameter at node; n = node length. ( C ) Genotype-dependent quantification of node length. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.6324. ( D ) Genotype-dependent quantification of paranode length. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.1927. ( E ) Ratio of node length and axonal diameter. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.5966. ( F ) Ratio of paranode length and axonal diameter. Not significant (n.s.) according to unpaired two-tailed t-test; n = 4–5 mice per genotype; p=0.4603.

    Article Snippet: Antibodies were specific for ANLN (Acris AP16165PU-N; 1:200), SEPT7 (IBL18991; 1:1000), SEPT8 (ProteinTech Group 11769–1-AP; 1:500), TUJ1 (Covance MMS-435P; 1:1000), neurofilament (Covance SMI-31; 1:1500), myelin-associated glycoprotein (MAG clone 513; Chemicon MAB1567; 1:50), voltage-gated sodium channel Na v 1,6 (alomonelabs ASC-009; 1:500) or contactin-associated protein (CASPR; Neuromabs 75–001; 1:500).

    Techniques: Immunohistochemical staining, Marker, Two Tailed Test